Helmut Butzkueven Selected Research

Crush Injuries

1/2016

Blocking LINGO-1 in vivo reduces degeneration and enhances regeneration of the optic nerve.

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Helmut Butzkueven Research Topics

Disease

96	Multiple Sclerosis 04/2024 - 05/2002
41	Relapsing-Remitting Multiple Sclerosis 12/2023 - 10/2012
9	Demyelinating Diseases (Demyelinating Disease) 03/2016 - 05/2006
8	Autoimmune Diseases of the Nervous System 04/2023 - 01/2019
8	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2019 - 04/2008
6	Disease Progression 08/2023 - 01/2011
5	COVID-19 01/2024 - 01/2021
5	Progressive Multifocal Leukoencephalopathy 04/2023 - 04/2016
5	Optic Neuritis (Retrobulbar Neuritis) 03/2022 - 01/2013
4	Neoplasms (Cancer) 02/2024 - 01/2021
3	Chronic Progressive Multiple Sclerosis 11/2023 - 01/2019
3	Atrophy 10/2023 - 07/2019
3	Infections 10/2023 - 01/2021
3	Encephalitis (Encephalitis, Rasmussen) 09/2022 - 04/2022
3	Tremor (Tremors) 02/2022 - 07/2012
2	Lymphopenia (Lymphocytopenia) 10/2023 - 01/2018
2	Cognitive Dysfunction 05/2023 - 01/2023
2	Seizures (Absence Seizure) 01/2023 - 01/2020
2	Glioma (Gliomas) 07/2022 - 05/2022
2	Genetic Predisposition to Disease (Genetic Predisposition) 05/2022 - 04/2010
2	Spontaneous Abortion (Miscarriage) 12/2020 - 02/2019
2	Inflammation (Inflammations) 05/2020 - 07/2013
2	Neuromyelitis Optica (Devic's Disease) 05/2020 - 02/2020
2	Autoimmune Diseases (Autoimmune Disease) 06/2014 - 12/2010
1	Herpes Zoster 10/2023
1	Transverse Myelitis (Necrotizing Myelitis) 03/2022
1	Drug Resistant Epilepsy 01/2022
1	Acquired CJD 01/2022
1	Stillbirth 12/2020
1	Premature Birth (Birth, Premature) 02/2019

Drug/Important Bio-Agent (IBA)

31	Natalizumab (Tysabri)FDA Link 04/2024 - 04/2014
25	Fingolimod Hydrochloride (FTY720)FDA Link 04/2024 - 04/2014
15	Biomarkers (Surrogate Marker)IBA 10/2023 - 12/2008
12	Cladribine FDA LinkGeneric 10/2023 - 10/2018
10	InterferonsIBA 03/2024 - 01/2013
10	Glatiramer Acetate (Copaxone)FDA Link 03/2024 - 03/2015
9	ocrelizumabIBA 03/2024 - 01/2020
8	Dimethyl FumarateIBA 02/2023 - 01/2019
6	Vitamin D FDA LinkGeneric 01/2024 - 12/2018
6	TabletsIBA 10/2023 - 10/2021
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 12/2010
5	AntibodiesIBA 01/2024 - 01/2016
5	Rituximab (Mabthera)FDA Link 01/2023 - 01/2020
4	Monoclonal AntibodiesIBA 01/2024 - 01/2017
4	Interferon-betaIBA 01/2023 - 04/2015
4	Myelin-Oligodendrocyte GlycoproteinIBA 03/2022 - 03/2007
4	Leukemia Inhibitory FactorIBA 01/2012 - 05/2006
3	teriflunomideIBA 02/2023 - 01/2019
3	Interferon beta-1a FDA Link 01/2023 - 01/2013
3	AutoantibodiesIBA 09/2022 - 05/2020
3	Type A Botulinum Toxins (Botox)FDA Link 02/2022 - 07/2012
3	Retinaldehyde (Retinal)IBA 01/2022 - 01/2013
3	Alemtuzumab (Campath)FDA Link 11/2021 - 01/2017
3	CuprizoneIBA 06/2015 - 04/2008
2	25-hydroxyvitamin DIBA 12/2023 - 01/2018
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 07/2022 - 04/2022
2	Leucine (L-Leucine)FDA Link 07/2022 - 05/2022
2	opicinumabIBA 12/2018 - 03/2017
2	c-Mer Tyrosine KinaseIBA 03/2016 - 01/2015
2	Phosphotransferases (Kinase)IBA 03/2016 - 01/2015
2	HLA-DRB1 Chains (HLA DRB1)IBA 03/2016 - 03/2007
2	tyrosine receptor (receptor, tyrosine)IBA 03/2016 - 01/2015
2	GalaninIBA 06/2015 - 09/2009
2	HLA Antigens (Human Leukocyte Antigens)IBA 10/2010 - 05/2002
1	Oxygen (Dioxygen)IBA 01/2024
1	cilgavimabIBA 01/2024
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2024
1	tixagevimabIBA 01/2024
1	ofatumumab FDA Link 01/2024
1	Therapeutic UsesIBA 12/2023
1	hydroxide ionIBA 12/2023
1	Cholecalciferol (Vitamin D3)FDA Link 12/2023
1	Gonadal Steroid Hormones (Sex Hormones)IBA 08/2023
1	Blood Proteins (Serum Proteins)IBA 01/2023
1	ProteomeIBA 01/2023
1	Surface Antigens (Surface Antigen)IBA 09/2022
1	Aminobutyrates (Aminobutyric Acid)IBA 07/2022
1	1,3-dipropyl-8-phenylxanthineIBA 07/2022
1	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 07/2022
1	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 05/2022
1	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 04/2022
1	Codon (Codons)IBA 01/2022
1	siponimodIBA 11/2021
1	SolutionsIBA 09/2021
1	Complement System Proteins (Complement)IBA 01/2021
1	incobotulinumtoxinA FDA Link 05/2020
1	Immunoglobulin G (IgG)IBA 02/2020
1	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2020
1	GlucocorticoidsIBA 01/2019

Therapy/Procedure

58	Therapeutics 04/2024 - 09/2004
11	Immunotherapy 11/2023 - 01/2013
6	Injections 04/2024 - 07/2012
3	Immunomodulation 02/2024 - 04/2016
2	Induced Abortion (Induced Abortions) 12/2020 - 02/2019
2	Aftercare (After-Treatment) 01/2016 - 07/2012
1	Off-Label Use 04/2024
1	Withholding Treatment 12/2022
1	Ambulatory Care (Outpatient Care) 08/2020
1	Intramuscular Injections 05/2020